Wednesday, 28 November 2012

New studies show effects of mammography guideline changes

New studies show effects of mammography guideline changes [ Back to EurekAlert! ] Public release date: 27-Nov-2012
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Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

CHICAGO Researchers assessing the impact of revised guidelines for screening mammography issued by the U.S. Preventive Services Task Force (USPSTF) found evidence that the new recommendations may lead to missed cancers and a decline in screening, according to two studies presented today at the annual meeting of the Radiological Society of North America (RSNA).

Routine screening mammography has traditionally been recommended by both the USPSTF and the American Cancer Society for all women over the age of 40. In 2009, the USPSTF issued controversial new guidelines recommending routine screening with mammography every two years for women 50 to 74 years old. In the studies being presented at RSNA 2012, researchers analyzed the impact of the new guidelines on women between the ages of 40 and 49 and the Medicare population.

"Recommendations on screening mammography are extremely important public policy and we wanted to contribute to that dialogue," said Elizabeth Arleo, M.D., assistant professor of radiology at New York Presbyterian Hospital Weill Cornell Medical College in New York City. "We get questions all day long from patients and referring physicians on the appropriateness of screening mammography. The inconsistent information is very confusing for everyone."

For her study, Dr. Arleo and a team of researchers analyzed data on screening mammography at New York Presbyterian Hospital Weill Cornell Medical College between 2007 and 2010. Over the four years, 43,351 screening exams were performed, which led to the detection of 205 breast cancers.

"Nearly 20 percent of cancers detected with screening mammography were found among women in their 40s, Dr. Arleo said. "It seems unacceptable to potentially miss nearly 20 percent of the breast cancers we are identifying. This, in our view, would represent a substantial degree of under-diagnosis."

Of the women screened in the study, 14,528, or 33.5 percent, were between the ages of 40 and 49. Of the 205 breast cancers detected, 39 (19 percent) were found in the 40-49 age group. Of those cancers, more than 50 percent (21 of 39) were invasive. Only three of the women between the ages of 40 and 49 diagnosed with cancer had a first-degree relative with pre-menopausal cancer.

"Our data favor the American Cancer Society recommendations of annual mammograms starting at age 40," Dr. Arleo said.

In the second study, a team of researchers analyzed data from The Medicare Part B Physician/Supplier Procedure Summary Master Files for 2005-2010. They calculated the following annual utilization rates for screening mammography per 1,000 female Medicare beneficiaries: 2005, 311.6; 2006, 312.4; 2007, 316.2; 2008, 320.1; 2009, 322.9; and 2010, 309.1.

From 2005 to 2009, the compound annual growth rate for screening mammography utilization was 0.9 percent, compared to a 4.3 percent decline in the utilization rate from 2009 to 2010.

"There was considerable controversy over the task force guidelines, but it was unclear how much they would influence women's choices about screening," said David C. Levin, M.D., professor and chairman emeritus of the Department of Radiology at Thomas Jefferson University Hospital in Philadelphia. "We're not able to tell from the data whether this significant drop in utilization was a result of women deciding to wait another year to have their mammogram, or women over the age of 74 not having the exam. But, clearly, the new USPSTF guidelines have had an effect."

Dr. Levin said the drop in the mammography utilization rate is especially concerning, given that the 2009 rate of 322.9 per 1,000 women wasn't particularly high.

"We'll never see 1,000 out of 1,000 women getting a screening mammogram, but you'd like to see that number closer to 1,000, and certainly higher than 322," he said. "We need to continue to follow these numbers and to watch the breast cancer mortality statistics."

###

Coauthors of Dr. Arleo's research are Melissa B. Reichman, M.D., Ruth Rosenblatt, M.D., Kemi T. Babagbemi, M.D., and Brittany Zadek Dashevsky, M.D., Ph.D.

Coauthors of Dr. Levin's research are Andrea J. Frangos, M.P.H., Vijay M. Rao, M.D., Laurence Parker, Ph.D., and Richard Sharpe, M.D., M.B.A.

Note: Copies of RSNA 2012 news releases and electronic images will be available online at RSNA.org/press12 beginning Monday, Nov. 26.

RSNA is an association of more than 50,000 radiologists, radiation oncologists, medical physicists and related scientists, promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill.

Editor's note: The data in these releases may differ from those in the published abstract and those actually presented at the meeting, as researchers continue to update their data right up until the meeting. To ensure you are using the most up-to-date information, please call the RSNA Newsroom at 1-312-949-3233.

For patient-friendly information on mammography, visit RadiologyInfo.org.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


New studies show effects of mammography guideline changes [ Back to EurekAlert! ] Public release date: 27-Nov-2012
[ | E-mail | Share Share ]

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

CHICAGO Researchers assessing the impact of revised guidelines for screening mammography issued by the U.S. Preventive Services Task Force (USPSTF) found evidence that the new recommendations may lead to missed cancers and a decline in screening, according to two studies presented today at the annual meeting of the Radiological Society of North America (RSNA).

Routine screening mammography has traditionally been recommended by both the USPSTF and the American Cancer Society for all women over the age of 40. In 2009, the USPSTF issued controversial new guidelines recommending routine screening with mammography every two years for women 50 to 74 years old. In the studies being presented at RSNA 2012, researchers analyzed the impact of the new guidelines on women between the ages of 40 and 49 and the Medicare population.

"Recommendations on screening mammography are extremely important public policy and we wanted to contribute to that dialogue," said Elizabeth Arleo, M.D., assistant professor of radiology at New York Presbyterian Hospital Weill Cornell Medical College in New York City. "We get questions all day long from patients and referring physicians on the appropriateness of screening mammography. The inconsistent information is very confusing for everyone."

For her study, Dr. Arleo and a team of researchers analyzed data on screening mammography at New York Presbyterian Hospital Weill Cornell Medical College between 2007 and 2010. Over the four years, 43,351 screening exams were performed, which led to the detection of 205 breast cancers.

"Nearly 20 percent of cancers detected with screening mammography were found among women in their 40s, Dr. Arleo said. "It seems unacceptable to potentially miss nearly 20 percent of the breast cancers we are identifying. This, in our view, would represent a substantial degree of under-diagnosis."

Of the women screened in the study, 14,528, or 33.5 percent, were between the ages of 40 and 49. Of the 205 breast cancers detected, 39 (19 percent) were found in the 40-49 age group. Of those cancers, more than 50 percent (21 of 39) were invasive. Only three of the women between the ages of 40 and 49 diagnosed with cancer had a first-degree relative with pre-menopausal cancer.

"Our data favor the American Cancer Society recommendations of annual mammograms starting at age 40," Dr. Arleo said.

In the second study, a team of researchers analyzed data from The Medicare Part B Physician/Supplier Procedure Summary Master Files for 2005-2010. They calculated the following annual utilization rates for screening mammography per 1,000 female Medicare beneficiaries: 2005, 311.6; 2006, 312.4; 2007, 316.2; 2008, 320.1; 2009, 322.9; and 2010, 309.1.

From 2005 to 2009, the compound annual growth rate for screening mammography utilization was 0.9 percent, compared to a 4.3 percent decline in the utilization rate from 2009 to 2010.

"There was considerable controversy over the task force guidelines, but it was unclear how much they would influence women's choices about screening," said David C. Levin, M.D., professor and chairman emeritus of the Department of Radiology at Thomas Jefferson University Hospital in Philadelphia. "We're not able to tell from the data whether this significant drop in utilization was a result of women deciding to wait another year to have their mammogram, or women over the age of 74 not having the exam. But, clearly, the new USPSTF guidelines have had an effect."

Dr. Levin said the drop in the mammography utilization rate is especially concerning, given that the 2009 rate of 322.9 per 1,000 women wasn't particularly high.

"We'll never see 1,000 out of 1,000 women getting a screening mammogram, but you'd like to see that number closer to 1,000, and certainly higher than 322," he said. "We need to continue to follow these numbers and to watch the breast cancer mortality statistics."

###

Coauthors of Dr. Arleo's research are Melissa B. Reichman, M.D., Ruth Rosenblatt, M.D., Kemi T. Babagbemi, M.D., and Brittany Zadek Dashevsky, M.D., Ph.D.

Coauthors of Dr. Levin's research are Andrea J. Frangos, M.P.H., Vijay M. Rao, M.D., Laurence Parker, Ph.D., and Richard Sharpe, M.D., M.B.A.

Note: Copies of RSNA 2012 news releases and electronic images will be available online at RSNA.org/press12 beginning Monday, Nov. 26.

RSNA is an association of more than 50,000 radiologists, radiation oncologists, medical physicists and related scientists, promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill.

Editor's note: The data in these releases may differ from those in the published abstract and those actually presented at the meeting, as researchers continue to update their data right up until the meeting. To ensure you are using the most up-to-date information, please call the RSNA Newsroom at 1-312-949-3233.

For patient-friendly information on mammography, visit RadiologyInfo.org.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-11/rson-nss111612.php

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Interpol Conducts 'War' on Poaching in Africa (Voice Of America)

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Amateur's Guide To Death and Dying

That that I?ve brightened up your day, let me tell you about my guest tomorrow (Tuesday) afternoon on the Puffman Show. He?s Dr. Richard Wagner out in Seattle, Washington?s & Dr. Wagner?s written a new interactive workbook designed to help us define & achieve a good death for ourselves. Loosely quoting the late Jim Morrison from the Doors, ?Nobody gets out of here alive? & ?The Amateur?s Guide To Death & Dying: Enhancing the End of Life? is a fascinating & useful new tool to help us address the questions & emotions that arise as we face our mortality. It?s designed primarily for sick, elder, & dying people & I?ll be giving away a copy of the book right after tomorrow?s afternoon?s interview with Dr. ?Gloom & Doom?. Dr. Wagner promises to address ?Why Me? The difficulty, as well as the necessity of, of facing & embracing our mortality. Although there are numerous other books available on this topic, nothing compares in scope, attitude, or style to this book. It?s modeled on a program that works & is highly praised by participants, their family, & friends & professionals who attend them. See you tomorrow afternoon at 4:35 for this timely & LIVELY discussion.

Source: http://ksenam.com/amaterus-guide-to-death-dying/

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Tuesday, 27 November 2012

Rice's star rises as congressional opposition dims

FILE - This April 14, 2012 file photo shows U.S. Ambassador to the United Nations Susan Rice speaking at U.N. headquarters. With congressional opposition softening, U.N. Ambassador Susan Rice could find her name in contention as early as this week to succeed Hillary Rodham Clinton as secretary of state. Her nomination to the top Cabinet job could signal the potential for a more robust intervention in world crises in President Barack Obama?s second term. (AP Photo/Craig Ruttle, File)

FILE - This April 14, 2012 file photo shows U.S. Ambassador to the United Nations Susan Rice speaking at U.N. headquarters. With congressional opposition softening, U.N. Ambassador Susan Rice could find her name in contention as early as this week to succeed Hillary Rodham Clinton as secretary of state. Her nomination to the top Cabinet job could signal the potential for a more robust intervention in world crises in President Barack Obama?s second term. (AP Photo/Craig Ruttle, File)

FILE - This Nov. 14, 2012 file photo shows Sen. John McCain, R-Ariz., the ranking member of the Senate Armed Services Committee, gesturing during a news conference on Capitol Hill in Washington. With congressional opposition softening, U.N. Ambassador Susan Rice could find her name in contention as early as this week to succeed Hillary Rodham Clinton as secretary of state. Her nomination to the top Cabinet job could signal the potential for a more robust intervention in world crises in President Barack Obama?s second term. (AP Photo/J. Scott Applewhite, File)

(AP) ? With congressional opposition softening, U.N. Ambassador Susan Rice could find her name in contention as early as this week to succeed Hillary Rodham Clinton as secretary of state. It's a step that may signal greater U.S. willingness to intervene in world crises during President Barack Obama's second term.

As Obama nears a decision on who should be the country's next top diplomat, Rice has emerged as the clear front-runner on a short list of candidates that many believe has been narrowed to just her and Sen. John Kerry, despite lingering questions over her comments about the deadly Sept. 11 attack on a U.S. Consulate in Libya.

According to congressional aides and administration officials, Rice will be making the rounds on Capitol Hill this week for closed door meetings with key lawmakers whose support she will need to be confirmed. Those appearances follow her first in-depth explanation of her Benghazi remarks that Republicans seized on as evidence of the administration's mishandling of the attack that took the lives of the U.S. ambassador to Libya and three other Americans.

Acting CIA Director Michael Morell will join Rice in her meetings with lawmakers.

A senior Senate aide said the administration was trying to measure the strength of the Republican opposition to a Rice nomination, sounding out the more moderate members of the Foreign Relations Committee such as Sen. Bob Corker, R-Tenn., who is in line to become the panel's top Republican next year, and Sen. Johnny Isakson, R-Ga.

Rice is scheduled to meet on Tuesday with Sen. John McCain, R-Ariz., her most vocal critic on Capitol Hill. She will also meet with Sen. Kelly Ayotte, R-N.H. McCain and Ayotte are members of the Armed Services Committee.

During an interview on Monday, McCain said he would ask Rice "the same questions I've been talking about on every talk show in America." Asked whether he thinks she's still unfit for secretary of state and what he was hoping for, McCain interrupted and said, "I'm not hoping for anything. She asked to see me and I agreed to see her."

Assessing the prospects for Rice before Obama makes any announcement would avoid the embarrassment of a protracted fight with the Senate early in the president's second term.

On talk shows the weekend following the attacks, Rice relied on talking points provided by the intelligence community that described the attack as a spontaneous assault growing out of a protest of an anti-Muslim film. GOP critics say her remarks downplayed evidence of an obvious terrorist attack just weeks before the Nov. 6 election.

Republicans called her nomination doomed, leading to a vigorous defense of her by Obama in his first post-election news conference. But since then, GOP lawmakers seemed to have softened their views. McCain, who said earlier this month that would he do everything in his power to scuttle a Rice nomination, said on Sunday that he was willing to hear her out before making a decision. McCain ally Lindsey Graham, R-S.C., has also eased his opposition and said he is usually deferential to presidential Cabinet picks.

Sen. Jim Inhofe, R-Okla., a member of the Foreign Relations Committee, had issued a statement highly critical of Rice on the day of Obama's news conference. He indicated Monday that perhaps she didn't know what had transpired in Benghazi on the day of the attack.

"I assumed she had full knowledge of everything that went on. I'm not at all convinced of that now. She very well could have been thrown under the bus," Inhofe said in an interview. He said she hadn't requested a meeting but he would be glad to meet with her.

White House spokesman Jay Carney said Monday that the administration appreciated McCain's latest comments about Rice, but wouldn't say whether the president saw them as an opening to make the nomination. "Ambassador Rice has done an excellent job at the United Nations and is highly qualified for any number of positions," Carney said.

Several diplomats currently serving with Rice said that what she lacked in Clinton's star power, she could make up with a blunter approach that demands attention and has marked her tenure thus far at the United Nations.

Rice, who at 48 is relatively young, has played the role of "conscience of the administration" on human rights and detainee issues and would bring "a certain edge" to the secretary of state job, according one colleague who has dealt with Rice on multiple issues over the past three years.

She "will not be going into the job as a star," said Karl Inderfurth, a former U.S. ambassador and senior State Department official who worked closely with Rice in President Bill Clinton's administration when she worked as a staff aide to the National Security Council and then as assistant secretary of state for African affairs. "She will be a rising star, though."

"Hillary Clinton understood the politics of diplomacy: what the person across the table needs in order to sell something," said Inderfurth, now at the Center for Strategic and International Studies think tank in Washington. "Susan Rice's background is different. What she'll bring is her experience in multilateral engagement and the limitations thereof."

"But the most important thing she brings to the table is her relationship with the president," Inderfurth said.

Rice, like many other foreign policy experts of her generation, was shaped by the Clinton administration's inability to prevent the genocide of hundreds of thousands of ethnic Tutsis and moderate Hutus in Rwanda 1994. Years later, she told a journalist: "I swore to myself that if I ever faced such a crisis again, I would come down on the side of dramatic action, going down in flames if that was required."

That doesn't mean the U.S. will change its policy of only providing humanitarian support to Syrian rebels fighting to overthrow the regime anytime soon. But Rice's confirmation as the next secretary of state could alter the balance in an administration that has viewed humanitarian interventions with significant skepticism, given its rejection of the Bush administration's war in Iraq.

An early supporter of Obama's 2008 presidential campaign, Rice fell out with some of her Clinton administration-era NSC and State Department colleagues who urged her to support Hillary Clinton's competing candidacy, including her own mentor, Madeleine Albright, and some of her top aides.

With the Clinton-Obama primary battle in full gear in April 2008, tension between the two camps was on public display at a ceremony and reception to unveil Albright's official portrait in the State Department's ornate 8th floor Benjamin Franklin room, according to several people present. At those events, Rice firmly brushed aside appeals that she switch allegiance, those present said.

Obama's 2008 election brought with it the prospect that Rice, one of his campaign's top foreign policy advisers, might be in line for the Cabinet job she is known to covet. Instead, however, Obama went with the surprise choice of Clinton and gave Rice the U.N. portfolio, although he attempted to deflect her disappointment by restoring the job to a Cabinet-level position.

But her sights remained set on the top job, according to people who know her.

Since arriving in New York, Rice can point to a series of diplomatic achievements ? most notably the NATO-led air campaign that toppled Libyan leader Moammar Gadhafi and tougher sanctions against Iran and North Korea over their nuclear programs.

But Rice has also been criticized ? along with other Security Council leaders ? for the failure of the U.N.'s most powerful body to take action to end the 19-month civil war in Syria.

She has also been criticized, especially by human rights groups, for being too protective of U.S. allies, namely Sri Lanka where the U.N. says up to 40,000 ethnic Tamil civilians may have been killed in the final months of the country's civil war that ended in May 2009, and Rwanda, which has been accused of backing the M23 rebel group that last week took control of the eastern Congo city of Goma.

As U.N. ambassador, she has gained a reputation for a sharp intellect and sharp elbows. She is not known for diplomatic finesse, rather for being aggressive ? sometimes too aggressive ? and using salty language on occasion. In private, she has a good sense of humor.

In a legendary exchange last December, Rice dismissed an appeal by Russia's U.N. Ambassador Vitaly Churkin, who also isn't afraid to speak out, for a Security Council investigation of civilian deaths in Libya from NATO's bombing campaign as "a cheap stunt" to distract attention from the Syrian conflict.

"Oh, the bombast and bogus claims," she told reporters.

Churkin responded by mocking Rice's Stanford University degree, saying: "We hear that the Obama administration wants to establish a dialogue with the international community in the United Nations... If this is the intention, really this Stanford dictionary of expletives must be replaced by something more Victorian."

___

Associated Press Writers Donna Cassata in Washington and Edith Lederer in New York contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2012-11-26-US-Cabinet-Rice/id-9fac599eb4a749b4b399de23de353cfc

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Lakad Pilipinas: PASAY CITY | Staycation at Microtel Mall of Asia

The Greece-Inspired Roof Deck of Microtel MOAI have been traveling almost non-stop the past few months and although I really love what I?m doing, being a travel junkie and all, it does get to you after a while. Constantly being on the road can be tiring.

And so when Microtel extended an invite for a mini vacation within the Metro, I didn?t even blink, I immediately grabbed the opportunity.

Microtel MOA FacadeI would be staycationing with a group of travelers; L of Anny?s Chocolate Skies, D of Tracking Treasures, C of Adventurous Feet, E of The Shade of Grey and J of The Backpack Chronicles. Relaxing with like-minded individuals would surely double the fun.

We entered the posh lobby of Microtel at five in the afternoon. Puffy white clouds sailing across Manila Bay were already being lit by the already setting sun. We immediately headed towards the roof deck of the hotel.

Sunset on the Roof Deck of Microtel MOAI was floored the moment we opened the door to the roof, it was as if I entered a warp zone into Santorini. Everything was painted in white; the floor, the trellises, the columns. The whites were offset by posh dark brown outdoor furniture which contrasts nicely with the theme. Potted palm trees and the panoramic view of the bay completed the illusion of Greece.

Microtel's Infinity Pool Looking Over Manila BayAt the center of the roof deck sits an infinity pool that looks out over the glimmering sea and the glittering lights of the city.

A couple lazily swam across the azure pool as the waning sun painted the heavens in contrasting shades of blues and oranges. I was almost tempted to jump in if not for our rooftop dinner (which I?ll tell you about on another post as it deserves its own article).

Mall of Asia's Fireworks Seen from the Roofdeck of MicrotelAfter watching the weekend fireworks lit the night sky, countless stories, non-stop picture taking of the food and being treated to one of the best dinner I?ve ever had. It was time to bed down for the night.

Microtel's Modern and Spacious RoomsWe were given rooms facing the city and the MOA Eye is clearly framed on the window. The room is spacious; two queen-sized beds, a vanity table and a closet leave more than enough space to run around in. And although the bed looks tempting, my favorite spot is the bay window.

Microtel's Clean and Modern Toilet and BathMost guests, especially the ladies, are particular when it comes to the toilet and bath and Microtel?s own wouldn?t disappoint. The fittings are modern, hot water is available and most importantly it is very very clean. The one thing I particularly like about it is their rain-type shower.

Early Evening at Microtel's Roof DeckI was planning on shooting the sunrise the next day but I guess Microtel?s comfort got the best of me. I overslept and got zero sunrise photos from the roof deck. Well, I guess I really got what I came here for, it is a staycation after all.MOA's The Eye from Microtel's Roof Deck

Microtel Mall of Asia
Address: Coral Way Ave. corner Seaside Boulevard
SM Mall of Asia Complex, Pasay City
Telephone: (02) 403-3333 | (0917) 5905914
Rates & Reservation: Click Here
Email: sales@microtel.ph
Website: http://www.microtel-manila.com/ppc/
GPS Coordinates: 14.530535,120.980275
View Location on Google Maps: Click Here

SPECIAL THANKS TO MICROTEL FOR SPONSORING MY OVERNIGHT STAY AT THEIR MALL OF ASIA BRANCH

Source: http://www.lakadpilipinas.com/2012/11/pasay-city-staycation-at-microtel-mall.html

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Monday, 26 November 2012

Richard's Real Estate and Urban Economics Blog: What is Apple's ...

Walter Isaacson's biography of Steve Jobs is a lot of fun--at least in part because it is not a hagiography.

One of the most striking things about the book is that Jobs never pushed profit maximization per se--he pushed "great products." ?When John Scully pushed out Jobs and ran the company, he did push profit maximization--and Apple nearly went out of business. ?Re-enter Jobs with his products-first philosophy, and Apple eventually becomes the most valuable company in history.

When economists model firms, we inevitably assume profit maximization, and then allow firms to compete either through price or quality. ?The exception to this is a principal-agent set-up, where managers are seeking to maximize their own compensation. ?But this doesn't really work for Apple, where Jobs was both a principal and an agent.

Maybe none of this matters--that making great products is a sufficiently strong proxy for profit maximization. ?But Job's desire to make great products led him to care a lot less about cost minimization than, say, Dell--the chapter on how fanatical Jobs was about the plastic case molding for the original Macintosh underscores how Jobs tended not to think about marginal revenue and marginal cost when making decisions.

Source: http://real-estate-and-urban.blogspot.com/2012/11/what-is-apples-objective-function.html

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